Tramadol: Limited Pain Relief, Doubled Serious Risk
A major review finds the common opioid tramadol offers minimal pain relief while more than doubling the risk of serious adverse events like heart problems. Doctors urged to reconsider its use.
A major review finds the common opioid tramadol offers minimal pain relief while more than doubling the risk of serious adverse events like heart problems. Doctors urged to reconsider its use.
President Trump signs an executive order classifying fentanyl as a weapon of mass destruction, linking it to a major military buildup and strikes in the Caribbean. Read the full analysis.
A Texas woman, 74, distributed enough fentanyl for 150,000 lethal doses via post in a 'side hustle' to afford her own medication. Discover the shocking details of the US drug trafficking case.
A mother-of-three and midwife was found dead after taking painkillers for chronic back pain. The Preston coroner recorded a conclusion of misadventure. Read the full story.
The NHS advises eight specific groups of people to consult a doctor before taking the common painkiller ibuprofen. Learn who is at risk and what the official guidance says.
NHS issues crucial guidance on paracetamol use. Discover the five key groups who should seek medical advice before taking this common painkiller to avoid serious health risks.
Discover how chemist John Lewis helped develop buprenorphine, a life-saving treatment for opioid addiction used by millions worldwide. Learn about his remarkable legacy.
Jackie Siegel's life transforms from building a 90,000-square-foot palace to Broadway musical fame while battling profound personal tragedies. Discover how she turns darkness into light.
A federal judge approves a $7bn settlement from the Sackler family over the opioid crisis. The deal directs funds to combat the epidemic and compensate victims. Discover the full implications.
A US judge is set to explain his approval of Purdue Pharma's opioid settlement, compelling the Sackler family to pay $7bn. Victims to receive compensation from 2025. Read the full details.
A US judge approves the Purdue Pharma settlement, compelling Sackler payouts and a company name change. Discover the key details and what it means for victims.
A US bankruptcy judge has approved a landmark $7bn settlement with OxyContin maker Purdue Pharma, requiring the Sackler family to pay victims and relinquish ownership. Discover the details.
OxyContin maker Purdue Pharma and Sackler family close to finalising landmark opioid settlement worth up to $7 billion after overwhelming support from claimants. Historic deal could end years of litigation.
Medical experts reveal surprising dangers of paracetamol misuse during cold season. Learn how to protect yourself from accidental overdose and liver damage.
Medical experts reveal why paracetamol shouldn't be your first choice for pain relief. Discover the hidden dangers and safer alternatives in this exclusive NHS health alert.
The NHS has issued a critical safety warning about ibuprofen after new research reveals potentially fatal side effects. Discover which patients are most at risk and what symptoms require immediate medical attention.
In a landmark meeting at the APEC summit, Donald Trump and Xi Jinping reach breakthrough agreement on combating fentanyl trade while addressing ongoing trade tensions between the world's largest economies.
Donald Trump's controversial comments about Tylenol safety have ignited fresh health concerns, as medical experts question his unexpected painkiller warning that's dividing opinion across the UK.
Medical professionals are sounding the alarm about dangerous side effects from mixing common painkillers, urging Brits to reconsider their approach to pain management.
The shocking trial of former LA Angels executive Eric Kay exposes baseball's troubling relationship with opioids and the devastating human cost behind the headlines.
Donald Trump suggests deploying naval forces against drug cartels in radical proposal to tackle America's fentanyl epidemic, drawing criticism from medical experts.
Los Angeles Angels superstar Mike Trout gives emotional court testimony about teammate Tyler Skaggs' opioid-related death, exposing baseball's hidden drug crisis
Los Angeles Angels superstar Mike Trout gives emotional testimony in wrongful death lawsuit surrounding teammate Tyler Skaggs' opioid overdose, revealing shocking details about clubhouse culture and prescription drug misuse in professional baseball.
Exclusive investigation reveals the silent crisis of brain injuries emerging from the opioid epidemic, with survivors facing lifelong neurological challenges and inadequate support systems across the UK.
A seemingly healthy university student died suddenly after taking paracetamol for minor pain, with his brothers racing to buy medication in a desperate bid to save him. The coroner's report reveals shocking details about the rare reaction that claimed Har
Exclusive analysis reveals stark regional disparities in drug-related fatalities across England and Wales, with northern cities bearing the heaviest burden of this growing public health emergency.
Medical experts reveal how common painkiller paracetamol could be putting your health at risk with regular use. Discover the hidden dangers and safer alternatives.
Exclusive investigation reveals alarming rise in drug-related fatalities linked to potent synthetic opioids called nitazenes, with deaths spreading across England and Wales.
A qualified pharmacist reveals why taking this everyday medication with certain health conditions could have catastrophic consequences. Essential reading for millions of UK households.
An in-depth look at The Guardian's major new series exposing the devastating human toll of America's overdose epidemic and the systemic failures fueling this public health catastrophe.