A Scottish mum's extreme fatigue, including sleeping for 24 hours, led to a life-threatening Addison's disease diagnosis after years of being told she had anxiety. Read her fight for answers.
A father from Corby issues an urgent warning after his healthy daughter, Sienna, 4, was diagnosed with Acute Necrotising Encephalitis following the flu. She faces a long hospital stay, missing Christmas.
Mikey Strachan, 13, has an undiagnosed condition requiring 24/7 care. Through the Mirror's Christmas appeal for Lifelites, virtual reality technology lets him play football and explore worlds.
A 95-year-old woman declared dead was found cooking in her kitchen six days later. Doctors diagnosed an 'artificial death'. Read this astonishing medical mystery.
A breakthrough NHS study reveals whole-genome sequencing provides diagnoses for rare genetic conditions two years earlier, offering families crucial answers and access to care. Read the inspiring story of three-year-old Nathaniel.
A breakthrough NHS study reveals whole genome sequencing is diagnosing rare genetic conditions in children two years sooner, transforming care for families like Nathaniel's in London.
Matthew Pascoe, 33, battles gastroparesis, vomiting up to 90 times daily. His life-saving device needs a £15,000 battery, but the NHS won't cover the cost. Read his story and learn how you can help.
Coronation Street actress Samia Longchambon opens up about living with Raynaud's disease for two decades. Discover her coping tips and how she manages the circulation condition.
Rugby league star Mark Riddell breaks down discussing daughter Ava's Ogden Syndrome, affecting just four children in Australia. Read his inspiring family story.
A Swansea mum is in a desperate race against time after her four-year-old son Tate was diagnosed with Sanfilippo Syndrome, a rare and terminal childhood dementia.
Emmy-winning actress Ruth Wilson opens up about her debilitating mystery illness and the frustrating five-year search for answers that led to a rare disease diagnosis.
Meet baby Ezra, the courageous infant born with amniotic band syndrome whose incredible survival story is capturing hearts across Britain after beating overwhelming medical challenges.
In an extraordinary medical breakthrough, 19-month-old Oscar Sparrow from West Midlands has been identified as the only person worldwide living with a never-before-seen genetic mutation, offering new hope for rare disease research.
A British woman's persistent dizziness and blackouts were initially dismissed as Long COVID, until a shocking diagnosis revealed a rare and potentially fatal heart tumour that required emergency surgery.
The devastating story of Sarah, a mother with rare dementia who can no longer recognise her own children, as her family fights for access to revolutionary treatment that could save her.
Ben Miller opens up about his daughter's life-changing diagnosis that forced him to leave the hit BBC series and prioritise family during their darkest hours.
Afshin Ghaderian, recognised as the world's shortest man at just 65cm tall, has passed away at age 27 after refusing to let his rare condition define his life's ambitions and dreams.
The heartbreaking story of Isabelle Tate, a young girl from England fighting Charcot-Marie-Tooth disease, a rare genetic condition threatening her ability to walk and enjoy a normal childhood.
A teenage girl's life has been shattered after NHS doctors repeatedly dismissed her symptoms as growing pains, only to discover she had a rare spinal condition that may leave her permanently unable to walk.
TV personality Kelly Osbourne breaks down while revealing her recent diagnosis with a rare neurological condition, sharing her fears and determination to raise awareness.
A scarce 2009 Kew Gardens 50p coin has sold for over double its face value in a recent auction, sparking renewed interest in coin collecting across the UK.
A Hampshire woman developed Foreign Accent Syndrome after suffering a stroke, causing her to speak with a Thai accent despite never visiting Thailand. Medical experts explain this rare neurological condition.
After two decades of being dismissed by doctors, a woman's persistent rash turned out to be a rare pre-cancerous condition requiring life-changing surgery.
A British woman shares her extraordinary medical journey after discovering a mysterious 2-inch growth on her body that doctors identified as a rare condition. Her story highlights the importance of trusting your instincts when something doesn't feel right
A mother's quick thinking led to the diagnosis of a life-threatening double aortic arch in her toddler after noticing unusual breathing patterns and a distinctive cough sound.
Exclusive: Mother's emotional journey as her son battles rare chromosome disorder and the family's desperate search for answers in the UK healthcare system.
The Biden administration makes unprecedented investments in Western rare earth companies to secure critical minerals and challenge China's market dominance in green technology.
A quick-thinking midwife's extraordinary observation during a routine appointment led to the discovery of a rare and life-threatening condition, saving an unborn baby from certain tragedy.
A young woman from Manchester lives in constant pain with a rare condition that causes her ribs to dislocate when she laughs, coughs or even breathes deeply, leaving her unable to work or enjoy simple pleasures.
Singer Anne-Marie opens up about her young son's harrowing health journey with a rare genetic disorder, sharing emotional details about hospital stays and the impact on family life.