Tammy Slaton Reveals Medication Error Triggered Mental Breakdown After Weight Loss
1000-lb Sisters star Tammy Slaton has publicly disclosed that she experienced a severe mental breakdown directly linked to being prescribed incorrect medication dosages following her dramatic weight loss transformation. The 39-year-old reality television personality shared these deeply personal mental health struggles during the latest episode of the TLC series that documents her journey.
Medication Dosage Not Adjusted for New Body Size
In her emotional confessional segment, Slaton explained that her prescribed depression medication remained at the same high dosage originally calibrated for her larger body, even after she had lost approximately 500 pounds. 'I went to the doctors. They did a bunch of blood work and my medication, it was such a high dose for my bigger body and now that I'm not so big, it was too high for my body size,' Slaton revealed during the broadcast.
The reality star described how this pharmacological mismatch plunged her into what she characterized as a 'manic depression state' that ultimately precipitated her mental breakdown. 'It just kind of put me in, I guess, a manic depression state and it was making me have a mental breakdown,' Slaton told viewers with notable candor about her distressing experience.
Medical Intervention and Ongoing Adjustment
Following medical consultation, healthcare professionals removed five prescriptions Slaton no longer required and significantly reduced the dosages of her remaining medications. According to the Mayo Clinic, bipolar disorder—historically termed manic depression—represents a mental health condition characterized by extreme mood fluctuations encompassing emotional highs (mania or hypomania) and profound lows (depression).
Slaton acknowledged that she continues adapting to her revised pharmaceutical regimen, confessing she doesn't yet feel completely like herself during this transitional period. The television personality sought professional intervention after her then-partner Andrea Dalton threatened to terminate their relationship due to concerning behavioral changes.
Describing the Psychological Turmoil
Elaborating on her mental state during this challenging chapter, Slaton described experiencing overwhelming stress and emotional volatility in recent months. 'Overwhelmed and just every emotion possible and when I was getting angry or mad,' she continued, 'I would black out and I would say things. It was me, but it wasn't me. I don't know how else to explain it.'
Fan Support and Recognition
Social media responses to Slaton's disclosure have been overwhelmingly supportive, with numerous followers expressing relief that she has taken proactive steps toward therapy and medical evaluation. One comment on TLC's official Instagram page stated: 'Glad to know she's taking all the advice about therapies and getting the physical side looked at as well.' Another user shared a parallel experience: 'That happened to me it was thyroid meds. Was too high making me nervous. I hope you feel better soon.'
Weight Loss Journey and Public Candidness
Tammy and her sister Amy achieved television fame when 1000-lb Sisters premiered on TLC in 2020, chronicling their substantial weight reduction efforts. Slaton has maintained remarkable transparency about her transformation, announcing in April 2025 that she had shed approximately 500 pounds. 'When I was at my heaviest, I was 700-plus pounds,' she disclosed on the series. 'Right now, I'm weighing in at 238.'
The reality star underwent bariatric surgery in late 2022, followed by subsequent skin removal procedures as part of her comprehensive weight management strategy. Her willingness to discuss both physical and mental health challenges continues resonating with audiences who have followed her journey from her heaviest weight exceeding 700 pounds to her current physical and psychological rehabilitation.
