NHS Issues Crucial Guidance on Common Antihistamine Chlorphenamine
NHS Guidance on Antihistamine Chlorphenamine

The National Health Service has issued updated advice regarding the use of chlorphenamine, a widely available antihistamine medication commonly found in brands like Piriton, Allerief, and Pollenase. This medication is frequently used to alleviate symptoms associated with allergies such as hay fever, as well as conditions including insect bites, eczema, conjunctivitis, and chickenpox. While it is accessible both on prescription and over the counter in pharmacies, certain individuals must exercise caution.

Who Should Seek Medical Advice Before Taking Chlorphenamine?

According to the NHS, most adults and children over the age of one can safely use chlorphenamine. However, there are twelve specific groups who should always consult with a doctor or pharmacist prior to use. This precautionary measure is essential to prevent adverse reactions and ensure patient safety.

Key Groups Advised to Proceed with Caution

The NHS highlights the following individuals who must speak with a healthcare professional before taking chlorphenamine:

  • Anyone who has experienced an allergic reaction to chlorphenamine or any other medication in the past.
  • Individuals diagnosed with primary angle closure glaucoma, a specific eye condition.
  • Those who have taken monoamine oxidase inhibitor antidepressants within the last fourteen days.
  • People suffering from urinary issues or difficulties in emptying their bladder.
  • Patients with epilepsy or other health problems that may lead to fits or seizures.
  • Individuals with breathing difficulties, such as asthma or other lung conditions.
  • Anyone with heart disease or severely high blood pressure.
  • Men who have an enlarged prostate.
  • Patients with liver or kidney problems.
  • Those scheduled for an allergy test, as chlorphenamine can affect results; stopping the medication a few days prior may be necessary.
  • People who must avoid alcohol, as some liquid formulations contain small amounts.
  • Frail older adults, who may be more susceptible to side effects like confusion.

Important Usage Instructions and Precautions

The NHS emphasises that if chlorphenamine has been prescribed, patients should strictly follow their doctor's instructions regarding dosage and timing. For those purchasing it from a pharmacy, it is crucial to adhere to the packet instructions or seek advice from a pharmacist. If symptoms do not improve within a few days, consulting a doctor is recommended.

Potential Drug Interactions to Monitor

Chlorphenamine can interact with other medications, potentially worsening side effects. The NHS advises checking with a healthcare provider if taking:

  • Monoamine oxidase inhibitor antidepressants, such as phenelzine.
  • Phenytoin, an anti-epilepsy medicine.
  • Medications for anxiety or sleep aids.
  • Any drugs that cause drowsiness, dry mouth, or urinary difficulties.

It is also noted that children under six should not take cough or cold medicines containing chlorphenamine alongside other ingredients. For a comprehensive list of interactions, patients are directed to review the leaflet inside their medicine packet.

Safe Combinations and Side Effects

Chlorphenamine is generally safe to take with common painkillers like paracetamol or ibuprofen. However, combining it with codeine-based painkillers, such as co-codamol, may increase the risk of side effects. The medication typically begins to work within thirty minutes to an hour, and users should wait at least four hours before taking another dose.

Common Side Effects and Safety Tips

Typical side effects of chlorphenamine include nausea, dizziness, headaches, sleepiness, blurred vision, and difficulty concentrating. Individuals experiencing dizziness, sleepiness, or blurred vision should avoid activities like cycling or driving until symptoms subside. Additionally, alcohol consumption should be avoided while taking this medication to prevent compounded effects.

For further detailed information, the NHS website provides comprehensive resources on medication safety and usage guidelines.