The NHS has issued a direct and important reminder to Britons using prescription medications to aid weight loss, stressing that the drugs are effective tools but "not a magic cure" on their own.
In a social media post on platform X on 13 January 2026, the national health service emphasised that long-term success hinges on combining the medicines with two fundamental lifestyle changes. This advice is aimed at users of GLP-1 inhibitor drugs, such as semaglutide, which work by suppressing appetite.
The Two Non-Negotiable Lifestyle Rules
The NHS was unequivocal in its guidance. To maximise the benefits of weight management medications, patients must integrate the following habits into their daily routine.
Firstly, adopting a calorie-reduced, high-protein diet is essential. Secondly, regular strength-building exercises are crucial for maintaining muscle mass and boosting metabolism. The health body explained that these medicines help by slowing stomach emptying and increasing feelings of fullness, thereby reducing calorie intake, but foundational lifestyle work is irreplaceable.
Which Medications Are Approved on the NHS?
While many drugs are trialled, only a select few are currently approved for weight management by the NHS. These include Orlistat, Liraglutide, Semaglutide, and Tirzepatide.
The NHS warns that these medications should only be used under strict clinical supervision and if prescribed by a doctor or pharmacist. "Never take a medicine for weight management if it has not been prescribed for you," the service stated, highlighting risks of serious side effects.
All approved treatments are designed to be used alongside a reduced-calorie diet and increased physical activity, not as a substitute for them.
The Scale of the Challenge
The reminder comes against a backdrop of significant public health concerns regarding weight in England. Official NHS figures from 2022 reveal that 29% of adults were classed as obese, with a further 64% categorised as overweight.
For individuals concerned about their weight, the first port of call should be their GP. A doctor can provide advice on safe weight management through diet and exercise and, if necessary, refer patients to specialist services.
These include local NHS weight management services or national programmes like the NHS Digital Weight Management Programme.
