Weekend Lie-Ins Linked to Higher Disease Risk, Major Study Reveals
Researchers have uncovered a precise, minute-by-minute guideline for optimal sleep duration across all seven days of the week, challenging the common belief that catching up on sleep at weekends is beneficial. A new study suggests that weekend lie-ins may actually be detrimental to health, particularly by increasing the risk of insulin resistance, a key precursor to type 2 diabetes.
Optimal Sleep Duration Identified
Academics set out to determine the ideal amount of nightly sleep required to ward off insulin resistance and to assess whether extra weekend sleep has any impact. They analysed data from over 23,000 US adults, examining their sleep patterns and estimated glucose disposal rate (eGDR), a measure of insulin resistance calculated from fasting blood sugar levels, waist circumference, and blood pressure.
Participants reported an average of seven and a half hours of sleep during weekdays, with nearly half (48%) admitting to catching up on sleep at weekends. The study found that the optimal sleep duration for avoiding insulin resistance is exactly seven hours and 19 minutes per night. Deviating from this amount, whether sleeping more or less, negatively affected eGDR levels.
Weekend Sleep: A Double-Edged Sword
Further analysis revealed nuanced effects of weekend catch-up sleep. For individuals sleeping less than the optimal amount during the week, one to two hours of extra weekend sleep was associated with higher eGDR, indicating some benefit. However, for those already meeting or exceeding the optimal weekday sleep, more than two hours of weekend catch-up sleep was linked to lower eGDR, signalling a greater risk of insulin resistance.
The authors concluded that weekend sleep compensation is "beneficial only in moderation and specifically for those with weekday sleep debt, whereas it may be detrimental for those who already sleep sufficiently." They advocate for more personalised sleep guidelines in clinical practice and public health, emphasising consistent, adequate sleep over weekend compensation.
Expert Insights and Practical Advice
Professor Naveed Sattar, an expert in cardiometabolic medicine at the University of Glasgow, commented on the findings, noting that ample evidence links shorter sleep—typically under seven hours per night—to a higher risk of developing type 2 diabetes. He explained that poor sleep disrupts appetite regulation, leading to increased food intake, and affects key hormones like stress hormones that influence glucose levels.
"Genetic studies also suggest that people predisposed to shorter sleep are at higher risk of future diabetes, strengthening the likelihood of a causal link," said Professor Sattar. He emphasised the importance of good sleep hygiene, including consistent bedtimes, a wind-down routine, and reduced screen use—especially from mobile phones—in the hour before bed.
The study, published in the journal BMJ Open Diabetes Research and Care, highlights the need for further research into the mechanisms behind sleep patterns and metabolic risk. It underscores that while occasional catch-up sleep might help those with sleep debt, relying on weekend lie-ins could pose health risks, particularly for metabolic health.



