A senior NHS pharmacist has issued an urgent alert to the millions of Britons taking atorvastatin, highlighting one critical side effect that must never be dismissed. The warning comes as the cholesterol-lowering drug solidifies its position as the most prescribed medication in England.
The Crucial Warning Sign: Muscle Pain That Persists
Peter Thnoia, Superintendent Pharmacist at the NHS-registered pharmacy PillTime, has provided clear guidance for patients. He explains that while some initial side effects may fade as the body adjusts, one symptom requires immediate attention. "Muscle pain that does not ease is the key early side effect to watch out for," Mr. Thnoia states. This discomfort, referred to as myopathy in the patient information leaflet, can range from mild to severe.
The pharmacist emphasises that any persistent muscle ache, especially if it worsens or begins to affect larger muscle groups, should be taken seriously. "When pain becomes significant enough to limit physical activity, it may indicate that an alternative treatment to atorvastatin is needed," he advises. In severe cases, the drug can lead to muscle fibre damage, making prompt reporting to a GP or prescriber essential. A GP may then conduct blood tests to assess the situation and determine if atorvastatin remains suitable.
Understanding the Benefits and Timeline
Amidst concerns about side effects, Mr. Thnoia also clarifies the positive impact atorvastatin can have. Patients can typically expect to see a significant drop in their cholesterol levels after about four weeks, which a blood test can confirm. Private testing is an option if an NHS test is not readily available.
However, the full health benefits take much longer to materialise. "Over several months to years, lower cholesterol will mean there's less fatty plaque building up in the arteries, so blood flows easier around the body," he explains. Combined with healthy lifestyle changes, this gradual process can lead patients to feel more energised and alert. Regular blood tests are recommended to monitor progress and confirm the treatment is working effectively.
Tolerability and Patient Management
With approximately eight million people across the UK now taking statins annually, according to the British Heart Foundation, frontline pharmacists are encountering more patients seeking advice. Tolerance to atorvastatin varies greatly from person to person, and there is no single factor that predicts an individual's response.
Mr. Thnoia, a registered pharmacist with the General Pharmaceutical Council with over 25 years of experience, offers reassurance: "If the first month of treatment passes without issues, it's likely that most people can continue taking the medication without difficulty." The fundamental advice for all patients is to thoroughly read the patient medication leaflet and to proactively flag any concerns with their GP to ensure side effects are properly monitored and managed.
