Pharmaceutical heavyweight Eli Lilly and Co. has unveiled plans for a substantial $3.5 billion manufacturing facility in Pennsylvania, marking a significant step in its broader domestic expansion strategy. The announcement, made on Friday 30 January 2026, underscores the company's commitment to boosting production capacity within the United States, driven by skyrocketing sales of its leading obesity and diabetes medications.
Strategic Expansion Across Multiple States
The Indianapolis-based drugmaker, renowned for producing weight-loss treatment Zepbound and diabetes drug Mounjaro, is actively expanding its domestic footprint. This new Pennsylvania plant joins a series of previously announced facilities in Texas, Virginia, and Alabama, with another currently under construction in Indiana. This multi-state approach highlights Eli Lilly's concerted effort to enhance its manufacturing capabilities and supply chain resilience across the nation.
Focus on Injectable Treatments in Fogelsville
The new facility will be located in Fogelsville, situated just outside Allentown, Pennsylvania. It is specifically designed to manufacture injectable drugs and associated devices. A key focus will be on producing retatrutide, an investigational once-weekly injectable weight-loss drug that remains under study and is not yet available for public use. This move positions Eli Lilly to capitalise on the growing market for advanced pharmaceutical delivery systems.
Construction Timeline and Economic Impact
Construction of the Pennsylvania plant is scheduled to commence this year, with completion targeted for 2031. The project represents a major investment in the region, promising to create jobs and stimulate local economic activity. This long-term commitment reflects the company's confidence in sustained demand for its innovative treatments.
Record Financial Performance Driven by Key Drugs
The expansion is fuelled by exceptional financial results. Eli Lilly reported a record third-quarter profit of $5.58 billion, propelled by robust sales of Zepbound and Mounjaro. Third-quarter revenue reached $17.6 billion, marking an increase of more than 50% compared to the same period the previous year. Notably, Zepbound and Mounjaro alone contributed $10 billion in sales during that quarter, demonstrating their dominant market position.
This strategic investment in Pennsylvania not only strengthens Eli Lilly's domestic production network but also aligns with broader industry trends towards localising pharmaceutical manufacturing. As demand for obesity and diabetes treatments continues to surge, the company is positioning itself to meet patient needs efficiently while driving future growth.