HOXD13 Protein Fuels Melanoma Growth, Suppresses Immune Response
International researchers discover that the HOXD13 protein is crucial for melanoma tumor growth and immune evasion, offering new treatment avenues for this deadly skin cancer.
International researchers discover that the HOXD13 protein is crucial for melanoma tumor growth and immune evasion, offering new treatment avenues for this deadly skin cancer.
Scientists are testing CRISPR gene-editing as a potential one-time treatment for high cholesterol, with early studies showing dramatic LDL reductions. However, experts warn of safety unknowns and stress current medications and lifestyle remain crucial for
New research from The Kinsey Institute shows that most people experience passionate love twice in their lifetime, challenging the 'one true love' narrative of classic films.
New research shows astronauts' brains move upward and backward in the skull during space missions, with longer stays causing greater shifts. Most changes return to normal within six months after returning to Earth.
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RecommendedAn 11-year-old boy's family outing in Wyoming led to the historic discovery of a near-perfect 48-million-year-old turtle fossil, now named 'Little Timmy'.
University of Maryland scientists use smart underwear sensors to discover people fart 32 times daily on average, far more than previously thought, with extreme variations between individuals.
A podcast revisits the question of whether evolutionary theory requires updating in light of modern scientific discoveries and debates.
A new scientific critique challenges a study claiming the Shroud of Turin is a medieval forgery, reigniting the centuries-old debate over the relic's mysterious origins.
A small copper-alloy artefact, long overlooked in a museum collection, has been identified as the world's earliest known metal drill, pushing back the timeline for advanced rotary drilling technology by over two millennia.
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RecommendedArchaeology students discovered a 9th-century mass grave containing remains of an unusually tall man who underwent trepanation, offering new insights into Viking-era conflicts and medical practices.
Newly released documents detail Jeffrey Epstein's close ties to the scientific community, revealing his cultivation of relationships with scientists and his interests in their work.
A study of over 130,000 people found habitual coffee or tea drinkers had a 15-20% lower dementia risk. Researchers caution more evidence is needed.
New research identifies beta-sitosterol in aloe vera as a potential Alzheimer's treatment, targeting enzymes linked to memory loss and cognitive decline in the UK's most common dementia.
Scientists have created the most complete skeletal model ever of a 10-metre-long 'dinosaur-killer' crocodile that terrorised prehistoric waters 76 million years ago.
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RecommendedA remarkably preserved 125-million-year-old fossil from China, named Haolong dongi, provides scientists with an unprecedented look at dinosaur skin at the cellular level, featuring unique spikes never before documented.
Groundbreaking research reveals a specialised diet combined with steroids could slow glioblastoma tumour growth by exploiting a metabolic weakness in cancer cells.
Scientists discover a 'hidden vulnerability' in glioblastoma involving vitamin B3 metabolism, suggesting a prescribed diet combined with steroids could slow tumour growth in this aggressive brain cancer.
Groundbreaking research reveals a metabolic weakness in glioblastoma tumours that can be targeted through specialised dietary approaches combined with steroid treatments.
New analysis of satellite imagery reveals ancient riverbeds in Saudi Arabia and Iran that scholars believe may correspond to the lost rivers Pishon and Gihon from the Garden of Eden narrative in Genesis.
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RecommendedA King's College London study reveals theobromine, a compound in dark chocolate, is associated with a younger biological age than chronological age in participants.
Professor Scott Solomon's new book explores how living on Mars might shrink humans, weaken immune systems, and complicate childbirth, raising doubts about Elon Musk's 2050 settlement vision.
A mathematical analysis of Old Testament prophecies fulfilled by Jesus reveals odds of one in 10 followed by 157 zeros, a number exceeding all electrons in the observable universe.
A single elephant bone discovered in Spain provides the first physical evidence that Hannibal really did lead war elephants over the Alps during the Second Punic War, challenging centuries of historical debate.
Significant funding cuts to particle physics, astronomy, and nuclear physics grants in the UK are driving early career researchers overseas, with experts warning of a catastrophic loss of talent and innovation.
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RecommendedArchaeologists in Turkey have found the first physical evidence that ancient Romans used human excrement to treat ailments, analysing a 2,000-year-old glass vial containing faecal biomarkers and thyme.
Neuroscientist Dr Tara Swart explains how focusing on someone's left eye during conversation can trigger primal bonding mechanisms and create deeper emotional connections.
Researchers have successfully recreated perfumes used in ancient Egyptian mummification, offering new insights into historical rituals and medicine through advanced VOC analysis.
A new study reveals that menstrual blood collected via a sanitary pad strip can detect HPV with high accuracy, potentially providing a non-invasive, convenient home alternative to traditional cervical screening methods.
Archaeologist Steve Dickinson claims a hill on the west Cumbrian coast may be the long-sought burial mound of Ivarr the Boneless, a formidable ninth-century Viking leader who led the Great Heathen Army.
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RecommendedArchaeologists have revived 3,500-year-old fragrances used in Egyptian mummification, creating scented cards and stations for multisensory museum displays in Germany and Denmark.